Supporters of the Atkins Diet claim that a low carbohydrate diet is a safe and effective method for losing weight. This article evaluates the low carbohydrate diet and specifically the claims made about ketosis.
The Low Carb-Ketosis Link
By severely limiting carbohydrates in your diet, the main energy source used by your body, glucose, drops to low levels. In return, insulin levels also drop. With low glucose and low insulin levels, the body turns to alternative sources of energy.
Because of a significant change in your body's chemistry when on the Atkins Diet, certain metabolic pathways are turned "on" that are normally not "on" or run at very low levels. One such pathway involves the breakdown of fat, called Beta-Oxidation of Fats.
Now, normally fats are broken down to produce energy when your body senses a need. But in the context of a low Carb diet, the normal breakdown pathway of fats is altered and an alternative pathway kicks in. This alternative pathway produces what are called ketone bodies.
Ketosis is the term used to describe when ketone bodies are circulating in your bloodstream. The ketone bodies can be used as alternative sources of energy by, most importantly, your brain.
In case you might be curious, the three ketone bodies produced by this alternative pathway for breaking down fat are acetoacetate, beta-hydroxybutyrate, and acetone. These ketone bodies are formed in your liver and then are transported to other tissues, mainly the brain. In your brain, they are converted back to a form that can provide direct energy during times of starvation.
Here is the whole process...
So, the Atkins Diet (and any low Carb diet) produces a low energy state (low glucose) that causes the breakdown fat using an alternative pathway that leads to the development of ketosis.
So far it sounds pretty good. By limiting Carbs in your diet, you can essentially force your body into breaking down stored fat, the very thing you need to get rid of to lose weight.
But there are problems...
Atkins Diet and Toxicity
Ketone bodies are toxic. Many supporters of low Carb diets claim that ketosis is safe. They state that they are natural byproducts of fat breakdown and even babies have high levels of circulating ketone bodies.
First, they are not natural by-products of fat metabolism. The normal beta-oxidation of fats does produce ketone bodies but these are incorporated into the normal cycle of energy production, called the Krebs cycle. When ketone bodies are circulating in your bloodstream, it signals an abnormal physiologic state, called starvation. They are not incorporated into the normal energy cycle, the Krebs cycle, and spill into the bloodstream.
Just because your body has the ability to transport ketone bodies to certain tissues and then use them for energy, does not make it a normal process. It is an alternative pathway that turns "on" only when your body is faced with depleted levels of the main energy source, glucose.
Secondly, babies are not small adults. A baby's liver and brain tissue are made up of different chemicals and pathways, specifically geared to handle the high fat diet coming from mother's milk. These pathways change as a baby grows and starts to eat other foods. Eventually, the normal adult pathways are set up and the infantile chemistry used as evidence to support the safety of ketosis, stop working.
But this is not even related to the fact that ketone bodies are toxic. In medicine, the three ketone bodies mentioned above are classified as toxic acidic chemicals. At high levels, they can cause your blood to become too acidic, a disease state called ketoacidosis.
Granted, this is rare because most of the ketone bodies will be used by the brain as an energy source. Ketoacidosis is usually seen in type 1 diabetics. It is a medical emergency.
So, is ketosis dangerous to your body? Yes and no. Yes, ketosis represents a state of starvation. Losing weight when the body thinks you're starving is the best way to guarantee weight regain. The weight will come back and come back as fat. No, ketosis will not cause ketoacidosis in non-diabetics. And as long as you have a large storage of fat, your brain will not starve for energy.
The Final Verdict
However, it is well known that microscopic damage can occur to the kidneys effecting their ability to filter the blood. But clinical signs of this damage may take several years to manifest. Chronic renal insufficiency is a concern for ketogenic dieters, which may cause problems in the years to come.
Conclusion
Atkins Diet and other ketogenic diets (low Carb) can be safe and effective in causing weight loss. However, I recommend keeping ketosis to a minimum and keep your carbohydrate intake above 50 grams a day. Don't follow the suggestions for reaching an "induction" phase. It's not necessary to turn "on" the alternative pathways described above and burn fat.
Remember, healthy weight loss is to burn fat and fat only. But it also involves keeping your rate of weight loss around 2-3 pounds/week. The induction phase promoted by the Atkins Diet can result in a rate of weight loss far greater than 2-3 pounds/week. It may sound good to you now, but how does gaining it all back as fat sound? Because that will happen if you lose weight too fast.
For more information on ways to experience healthy weight loss, visit
To Healthy Living!
Dr. Michael A. Smith
Chief Medical Consultant
Diet Basics Website
Dr. Smith is the Chief Medical Consultant to Diet Basics, a content rich weight loss site dedicated to all dieters fighting to lose weight. Please visit his site at...diet basics
One visit and you'll be convinced that Dr. Smith and Diet Basics is your on-line resource for healthy weight loss!
Have you ever thought, "I just can not seem to... Read More
Eating the right foods and exercising regularly have been the... Read More
At the University of Illinois, a new research found that... Read More
A diet may be a fad diet or a healthy... Read More
You've heard them before and may even have believed some... Read More
The act of taking the first step is what separates... Read More
In this issue, I am going to focus more on... Read More
World Health Organization has observed that obesity has now reached... Read More
In 1994, I had a RNY surgery. At 350 lbs... Read More
How to Say No When You Don't Want the FoodA... Read More
In the medical community, "obesity" is generally said to be... Read More
ObesityToday, 64.5 percent of adult Americans (about 127 million) are... Read More
When people hear the term Unified Theory, some times called... Read More
Getting enough of the good fats will help you lose... Read More
Do calories matter or do you simply need to eat... Read More
"I am going to start a diet tomorrow". How many... Read More
I had lost nearly fifty pounds before anyone mentioned my... Read More
Metabolism is the process by which your body changes food... Read More
What does it take to lose weight?When it comes to... Read More
We all know that weight loss is important. We know... Read More
More than 70% of US adults are overweight and that... Read More
Reading labels is an essential part of any weight loss... Read More
Supporters of the Atkins Diet claim that a low carbohydrate... Read More
For many years, the experts, including our government have been... Read More
Your Non-Conscious Mind is 98% of your full power.Your Inner... Read More
family-safe home cleaners Arlington Heights ..Fat Loss in GeneralThis morning I conducted a search engine... Read More
Mistake 1: Not changing your calorie plan as you lose... Read More
What is the relationship between intake of nutrition and metabolism... Read More
If you've been pursuing a lighter, healthier version of yourself,... Read More
Metabolism is the process by which your body changes food... Read More
Over the past 5 years, online weight loss programs have... Read More
No matter what the reason, successful weight loss and healthy... Read More
Losing weight is a lifelong commitment. It takes patience and... Read More
A very interesting story was reported recently by WebMD.com. A... Read More
Can You Lose Weight Where You Want?If you have excess... Read More
Whenever I hear someone say they just can't lose weight,... Read More
How to burn fat fast is a question that burns... Read More
Are you often overcome with an urge to splurge on... Read More
You gain weight when your calorie intake is more than... Read More
Liposuction works best with people who are a normal weight... Read More
I am considering Gastric bypass surgery because I am overweight,... Read More
People always ask me " how it is that your... Read More
An increasing trend over the last few years has been... Read More
Are you frustrated with your weight problem and don't know... Read More
If you're serious about losing weight and getting fit, you... Read More
What if by making a few small changes in your... Read More
As the holidays approach, a frequent question from my clients... Read More
Why has Phentermine stopped helping me lose weight?Many people are... Read More
A 'diet' is always seen as a temporary measure. An... Read More
What are the best fad diets? It's a question I'm... Read More
Weight Loss |